Have you ever felt your liver get cold? Or warm?

Probably not, right? We usually don't actively feel our liver, the way we can feel our hands for example. Still, our liver is wired with nerves, as you can see in the movie below. They form a beautiful fiber network expanding throughout the whole organ.

Nerves visualized in an adolescent mouse liver.

The nerves connect our liver with our brain, so both organs can "talk" to each other by sending and receiving signals. An important role for the nerves in the liver is to make sure our sugar levels in the blood remain constant.

The imaging and movie creation in IMARIS was performed by Elisabeth Verboven at the BIC facility at Karolinska Institutet (Sweden).